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![]() Curriculum VitaePersonal DataBornDecember 10, 1952 in Pasadena, California. Contact InformationEducationB.S., University of California at Davis Ph.D., Johns Hopkins University, 1980 Postdoctoral Fellow, University of Chicago, 1980-1981 Postdoctoral Fellow, Johns Hopkins University School of Medicine 1981-1985 < top > Professional AppointmentsResearch Associate, Department of Biophysics, Johns Hopkins University School of Medicine 1985- 1989. Assistant Professor, Department of Biochemistry, Case Western Reserve University School of Medicine, 1989-1998. Instructor in Physiology, Marine Biological Laboratory, Woods Hole, Massachusetts, 1989. Guest Assistant Biophysicist, Biology Department, Brookhaven National Laboratory, 1991-1993. Assistant Professor, Department of Physiology and Biophysics, Case Western Reserve University School of Medicine, 1994-1999. Associate Professor, Department of Biochemistry, Case Western Reserve University School of Medicine, 1998-1999. Research Scientist, Duke University Marine Laboratory, Nicholas School of the Environment, 1999- < top > Past and Present Research Support< top > Honors and AwardsIndividual National Research Service Award GM07985, Karen A. Magnus, Research Fellow, (Paul B. Sigler and Eaton E. Lattman, sponsors). 1980-1983. Minority Research Initiation Award NSF DMB90-04561, Karen A. Magnus, P.I. 1990-1993. < top > Bibliography< top > Teaching ActivitiesUndergraduate CoursesPhysical Properties of Macromolecules (Lectures on x-ray crystallography, structures and functions of proteins and nucleic acids, prediction of protein structures, folding and dynamics.) Enzymes (Lectures on structural mechanisms and regulation, kinases, NMR principles, metalloenzymes and serine proteases.) Undergraduate Biochemistry Seminar (Discussion of original literature on macromolecular structure, sickle cell anemia, respiratory physiology, vision and color blindness, yeast genetics, information technology, the double helix structure, protein synthesis.) Environmental Biochemistry (Ribosomal structure and functions.), (Three dimensional structures, data bases and software.) Graduate CoursesEnzymes (Demonstration of molecular graphics.) Cell Biology/Molecular Biology (Section Leader. Lectures on protein structure, protein folding, mechanisms of inhibition and drug design, kinetics and thermodynamics.) Chemistry and Properties of Proteins (Lectures on x-ray diffraction, protein structure, mass spectroscopy and nuclear magnetic resonance, mechanisms of protein folding.) Structure and Function of RNA (Lectures on RNA structures, x-ray diffraction, discussions of the current RNA literature.) Graduate StudentsHoa Ton-That, Ph.D. January, 1994. Thesis title: "The X-ray Crystal Structure of Subunit II Hemocyanin from the Limulus polyphemus in the Oxygenated State". Peter d'U. Proctor, Ph.D. June, 1998. Thesis title: "Crystallographic Studies of Transport Proteins and Ligands." Alvin Changco M.S. June, 1999. Structural studies of the L1 cell adhesion molecule with Dr. Vance Lemmon (Neurosciences). Dejan Zivkovic, M.S. August, 1998. "Molecular biology and sequences of the subunits of Limulus hemocyanin" with Dr. David Samols (Biochemistry). Postdoctoral FellowsDiane Peapus, Ph.D., 1994-5. Crystallization trials on cartilage link protein with Dr. Thomas Hering (Medicine). Crystal structure of a niobium propeller compound with Dr. Paul Challen gohn Carroll University). Shenping Liu, Ph.D., 1994-7. Crystal structure of profilin I. Crystal structures of fluoro-, azido, hydroxo- and nitrosyl forms of Limulus II hemocyanin. Other Teaching1989 Instructor at Marine Biological Laboratory, Woods Hole, Massachusetts. Physiology: Cell and Molecular Biology. Average 6 students for 20 days of 14 hours each. 1993 Instructor at University of Georgia, Athens, Georgia. NSF Inorganic Biochemistry Summer Workshop. 50 students for 4 days. 1995 Instructor of Horizons on Biomedical Science (Health Careers Enhancement for.Minorities) CWRU. 1996 Instructor of Horizons on Biomedical Science (Health Careers Enhancement for Minorities) CWRU. < top > Invited Research PresentationsProfessional Meetings
< top > Seminars
< top > Membership in Professional SocietiesAmerican Crystallographic Association
< top > Cover Illustrations Based on My ResearchMagnus, K.A., Ton-That, H. and Carpenter, J.E. (1994) Chem. Rev. 94: 727-735. Hazes, B., Magnus, K.A., Bonaventura, C., Bonaventura, J., Dauter, Z. Kalk, K. and Hol, W.G.J. (1993) Protein Science 2: 579-619. Decker, H. and Terwilliger, N. (2000) J. Exptl. Biol. 203: 1777-1782. < top > Ad hoc Reviewer For:The National Science Foundation, The Ohio Supercomputer Center, The Journal of Biological Chemistry, Journal of Physical Chemistry, Proteins: Structure, Function, and Genetics, Cell Calcium, Consiglio Nazionale delle Ricerche, Comitato per le Scienze Fisiche, Journal of Molecular Biology, Nature Structural Biology, Journal of Structural Biology, Acta Crystallographica, Archives of Biochemistry and Biophysics. Advisor to:Vakgroep Organische en Anorganische Chemie of the International Union of Pure and Applied Chemistry, Inorganic Chemistry Division. < top > |
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