logo: Karen Magnus image: Hemocyanin

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My laboratory studies Oxygen transport proteins using x-ray diffraction techniques.

Hemocyanin ("blue blood") is the protein that carries oxygen and other ligands inside the common horseshoe crab Limulus polyphemus.

Each molecule of hemocyanin is about 300Å (3x10-6cm) and comprises 48 subunits.

Key research findings are in the areas of

  1. How oxygen and other ligands bind to the dicopper binding site.
  2. Structures of different subunits.
  3. Cooperative mechanisms.

This material is based upon work supported by the National Science Foundation under Grant No. 0096006.

Any opinions, findings and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation (NSF).